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Correlación entre la amplitud de distribución eritrocitaria y los parámetros hematológicos e inflamatorios, en sujetos venezolanos con procesos infecciosos
Resumen
DOI: https://doi.org/10.53766/AcBio/2023.13.26.17
La amplitud de distribución eritrocitaria es un parámetro hematológico que mide la variabilidad del tamaño de los glóbulos rojos y clásicamente se ha utilizado para determinar el origen de las anemias, sin embargo, actualmente se ha asociado a enfermedades no hematológicas. El objetivo de esta investigación fue determinar si existe correlación entre la amplitud de distribución eritrocitaria y los parámetros hematológicos e inflamatorios, en sujetos venezolanos con procesos infecciosos. Fue un estudio piloto, transversal retrospectivo, donde se registraron los valores de velocidad de sedimentación globular, proteína C reactiva y parámetros hematológicos, de 48 sujetos (40,3 ± 16,2 años de edad), que acudieron al servicio de emergencia del Hospital Universitario de Caracas, los cuales fueron divididos según su estado infeccioso en dos grupos: G1 (sin proceso infeccioso aparente asociado) (n=28) y G2 (con proceso infeccioso) (n=20). Se encontró que sólo hubo diferencia estadísticamente significativa en el contaje de glóbulos blancos y la relación neutrófilo/linfocito (p< 0,05) entre G1 y G2; la amplitud de distribución eritrocitaria mostró correlación positiva con la velocidad de sedimentación globular (p< 0,01), la proteína C reactiva (p< 0,05) y la relación neutrófilo/linfocito (p< 0,05) en el G2, mientras que no mostró correlación con ningún parámetro en el G1. Se concluye que probablemente los procesos infecciosos condicionan a que exista correlación positiva entre la amplitud de distribución eritrocitaria y la velocidad de sedimentación globular, la proteína C reactiva y la relación neutrófilo/linfocito. Se sugiere dar continuidad a este estudio con un tamaño muestral mayor.
Recibido: 14/07/2023
Aceptado: 22/08/2023
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