Effect of Borax Honey on the growth of Candida Albicans, Isolated of patients with lesions of Subprotesic Stomatitis

Abstract

In the oral cavity, several pathologies are present, one of the most frequent is the subperitoneal stomatitis (ESP) of multifactorial etiology that affects with high prevalence of patients with total dentures and is frequently associated with Candida albicans. The traditional therapeutic behavior of ESP includes the elimination of local factors and the use of local and systemic antifungal agents, even when they are effective, can produce adverse effects and provoke microbial resistance, resulting in natural alternatives such as borax honey, widely used in And herpetic stomatitis. The purpose of this research was to compare the in vitro inhibitory effect of 3 brands of Borax honey on the growth of 15 strains of Candida albicans isolated from patients with ESP and a reference strain C. albicans CDC-385, Using fluconazole (Diflucan 100mg) and 0.2% chlorhexidine as controls, by means of the diffusion method in well agar. The obtained plates were incubated in areobiosis at 35 ° C for 24 hours. Measurement of inhibition halos in millimeters. When comparing the results of the three official formulations of borax honey with each other, a difference was found between the size of the inhibition halos generated by these three officinal formulas on the 13 strains evaluated, borax honey 1 generated a better inhibitory effect with Halos greater than 30mm, borax honey 3 with halos of 15 to 30mm and borax honey 2 with halos smaller than 15mm, with respect to fluconazole showed that 7 strains studied including the the reference strain CDC-385 showed antifungal resistance. Chlorhexidine 2% inhibited the growth of all strains of C. albicans studied, with inhibition halos ranging between 16mm and 23mm.